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Are deficits in selective attention, working memory, and executive function in persons with schizophrenia distinct impairments or different manifestations of one higher-order impairment?
How might digital interventions effectively improve the functional outcomes of individual with psychosis? A new study highlights both the promise and challenges of these emerging digital tools.
Up to 25-50% of patients with schizophrenia attempt suicide--a much greater proportion than in the general population. What are the risk factors for suicidal ideation and suicide in this group?
In this commentary, the authors outline shortcomings in the knowledge-base related to antipsychotic medications, highlighting disconnects between clinical trial results and real-life clinical use.
This study examined odor identification, discrimination, and detection threshold performance in newly diagnosed individuals across the psychosis spectrum compared with healthy controls.
This study evaluated the risk of developing emergent psychotic-disorders from clinical syndromes other than those usually considered at clinical high risk for psychosis.
This paper traces the evolution of the neurodevelopmental hypothesis of schizophrenia and the roads which led to the Developmental Risk Factor Model, linking risk factors to psychotic symptoms.
With a nod to the new Motor Systems RDoC construct, this paper explores current understanding of three key motor circuits and their functions in the context of psychiatric illnesses.
Does schizophrenia have an immunological basis? This study tested the hypothesis that common variation within immune genes contributes to schizophrenia.
This article discusses how a clinical investigator can engage RDoC methodology to explore the neurobiological underpinnings of psychopathology. How can research be formulated within RDoC's framework?
The author makes the case for the inclusion of care for people with schizophrenia in the basic package of services covered by universal health coverage.
A comprehensive, multidisciplinary, team-based treatment approach for first episode psychosis proved more costly than usual care in this study. Are the benefits achieved worth the additional cost?
