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Management of Epilepsy During Pregnancy: Evidence-Based Strategies
How should you counsel epileptic patients pre- and post conception? Read about the risks and benefits of available antiepileptic drugs, and which should be avoided during pregnancy, in this review.
May 05, 2015
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Conquering the Barriers: Are Antibody Therapeutics Feasible for CNS Indications?
Biologics have become an increasingly significant component of the therapeutic landscape, but delivery across the blood-brain barrier has proven challenging.
April 28, 2015
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Approach to the International Traveler With Neurological Symptoms
Returning international travelers may present with a myriad of neurologic symptoms, including confusion, headache, weakness and sensory symptoms. What should be your diagnostic approach?
April 16, 2015
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Human-Derived Natural Antibodies: Biomarkers and Potential Therapeutics
This article explores the nature of self-antigens and the development of human natural antibodies as therapeutics for disease, focusing on the IgM class active in neurological disorders.
March 16, 2015
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Identification of Toxic Neuropathies: Cardinal Tenets
What are systemic signs of toxin intoxication? Learn about the diagnosis and management of toxic neuropathy.
February 16, 2015
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Risk Factors for Suicide in Epilepsy Patients
Which patients with epilepsy are at risk for suicide? What are potential risk factors?
February 02, 2015
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Evolution of MRI of Brain Injury in Concussion Patients
Has diffusion tensor imaging given MRI a new role in evaluation of mild TBI?
January 19, 2015
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Neuroimaging Chronic Pain: What Have We Learned and Where Are We Going?
How does the brain work in the presence of chronic pain?
January 05, 2015
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Nonamyloid PET Biomarkers and Alzheimer's Disease: Current and Future Perspectives
Learn how PET biomarkers for neurodegeneration, neuroinflammation, and neurotransmission may improve Alzheimer's disease management.
December 22, 2014
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What Have Novel Imaging Techniques Revealed About Metabolism in the Aging Brain?
Brain metabolism is an important biomarker for aging and neurodegenerative disorders. What can the latest neuroimaging techniques tell us about the aging brain?
August 08, 2014
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Time to Open the Blood-Brain Barrier Gate for Biologics?
Recent advances in our understanding of the blood-brain barrier should allow for clinical investigations into the targeted delivery of biologic agents such as antibodies for brain disorders.
July 09, 2014
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The Potential Clinical Utility of Novel Methods for Peripheral Nerve Regeneration: Where Are We Now?
This brief review summarizes the current state of research into peripheral nerve regeneration following traumatic injury. Which approaches hold promise?
May 09, 2014
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Neuropathogenesis of Prion Disease
While much is known about the clinical pathology of prion diseases, their actual neuropathogenic process remains uncertain. How might prions do their damage?
April 10, 2014
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Deep-brain Stimulation for Dystonia
Deep-brain stimulation has shown to be an effective therapeutic option for dystonia, but not all types of dystonia may be equally responsive.
February 21, 2014
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Optimizing Mouse Models of Neurodegenerative Disorders
This review takes a look at the history of model development for neurodegenerative diseases. What has been learned which may improve the design, development and use of mouse models?
January 21, 2014
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Under- to Over-Eating
In this article, the authors put forth the hypothesis that eating disorders such as anorexia nervosa and bulimia could result from an impairment of serotoninergic systems.
December 04, 2013
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Neuronal Adhesion and Synapse Organization in Recovery After Brain Injury
In this article, the authors focus on the cellular and synaptic alterations that occur with traumatic brain injury. Could synaptic cell adhesion molecules be potential targets for future therapeutics?
October 18, 2013
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Neurostimulators for the Treatment of Primary Headaches
This review explores various neurostimulation modalities as options for treatment of patients with drug-resistant primary headaches. Which techniques have shown efficacy?
August 19, 2013
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Update on the Management of Subarachnoid Hemorrhage
This review presents current best practice in the management of subarachnoid hemorrhage, including emergency and critical care management, treatment of medical complications, and surgical options.
April 29, 2013
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Peptidergic Drugs for the Treatment of Traumatic Brain Injury
Cerebrolysin, a peptidergic drug with neuroprotective and neurorestorative properties, presents a novel, multimodal approach to the treatment of traumatic brain injury.
March 28, 2013