Nature Clinical Practice Rheumatology

Articles Available on Medscape

• Treating Skeletal Pain: Limitations of Conventional Anti-inflammatory Drugs, and Anti-neurotrophic Factor as a Possible Alternative
  Can nerve growth factor inhibitors be an effective alternative treatment for post-traumatic and post-operative skeletal pain, without impairing bone healing?

  February 10, 2009

• NICE Guidelines on Anti-tumor Necrosis Factor Therapy for RA
  This viewpoint explains the rationale and debate surrounding the NICE guidelines recommendation that patients in whom initial anti-TNF therapy is ineffective shouldn't switch to another TNF inhibitor.

  January 02, 2009

• Is Long-term Etanercept Therapy Safe and Effective in Patients With Juvenile Rheumatoid Arthritis?
  Juvenile rheumatoid arthritis can be difficult to treat, as not all traditional treatments are effective in patients. Can long-term etanercept therapy provide a safe and effective treatment option?

  December 04, 2008

• Relevance of Osteoproliferation as an Outcome Parameter in Ankylosing Spondylitis
  This viewpoint explores the relevance of osteoproliferation amongst other outcome parameters in akylosing spondylitis for monitoring the structural damage of the disease.

  November 19, 2008

• MicroRNAs, The Immune System and Rheumatic Disease
  MicroRNAs (miRNAs) have been implicated in the pathogenesis of rheumatic disease and are, therefore, a potential target for drug development. This review describes the well-established roles of miRNAs in hematopoiesis and the immune response.

  October 22, 2008

Table of Contents

2009 - 5 (3)

• New approaches for managing antiphospholipid syndrome. 

  March 01, 2009

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• Imaging the painful osteoarthritic knee joint: what have we learned? 

  March 01, 2009

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• Cardiac manifestations of neonatal lupus erythematosus: guidelines to management, integrating clues from the bench and bedside. 

  March 01, 2009

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• Time for new outcome measures in hand osteoarthritis? 

  March 01, 2009

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• Is spleen tyrosine kinase inhibition an effective therapy for patients with RA? 

  March 01, 2009

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• Is tocilizumab in combination with traditional DMARDs safe and effective for patients with active RA? 

  March 01, 2009

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• How do the efficacy and safety of abatacept and infliximab compare in the treatment of active RA? 

  March 01, 2009

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• Is arthroscopic surgery a beneficial treatment for knee osteoarthritis? 

  March 01, 2009

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• Pharmacologic therapy to reduce fracture risk: comment on the clinical practice guidelines of the ACP. 

  March 01, 2009

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• Available therapeutic options following failure of a first anti-TNF agent. 

  March 01, 2009

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• Clinical and radiographic response to a local infliximab injection in a patient with chronic sacroiliitis. 

  March 01, 2009

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• Certolizumab pegol--what role does this new TNF inhibitor have in the treatment of RA? 

  March 01, 2009

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• A new 5-lipoxygenase inhibitor seems to be safe and effective for the treatment of osteoarthritis. 

  March 01, 2009

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• Are static resting wrist splints beneficial in early RA? 

  March 01, 2009

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