From theheart.org on Medscape

Coverage from the

American College of Cardiology (ACC) 2018 Annual Scientific Session

March 10 - 12, 2018; Orlando, Florida

March 10 - 12, 2018 Orlando, Florida

ACC 2018 Barbershop-Based Healthcare Cuts Hypertension in Blacks An outreach program leveraging the community barbershop made impressive inroads combatting hypertension in black men, who have the highest hypertension-related death rate in the United States.
Medscape Medical News, March 12, 2018
ACC 2018 ODYSSEY: Alirocumab Cuts CV Events, All-Cause Death Post-ACS First evidence of survival benefit with PCSK9 inhibitor alirocumab reignites the call for greater access to these expensive drugs for patients not just with ACS but also with stable atherosclerotic CVD.
Medscape Medical News, March 10, 2018
ACC 2018 VEST: No Sudden Death Benefit Early Post-MI From LifeVest But defibrillators work by preventing sudden death, so it's a bit of a head-scratcher that all-cause mortality dropped instead for people who used the wearable defibrillator for 90 days after their MI.
Medscape Medical News, March 10, 2018

Meeting Highlights At A Glance

Top News From ACC 2018: Slideshow Highly anticipated results of the ODYSSEY Outcomes trial of a PCSK9 inhibitor featured prominently at this year's scientific sessions -- and didn't disappoint.

Conference News

ACC 2018 No Limb-Ischemia Wound-Healing Gains From Gene Therapy: STOP-PAD
Medscape Medical News, April 12, 2018
ACC 2018 NOTION: 5-Year TAVR vs SAVR Outcomes Similar in Low-Risk Patients
Medscape Medical News, April 9, 2018
ACC 2018 CardioMEMS Sensor Linked to Lower Mortality in Heart Failure
Medscape Medical News, March 27, 2018
ACC 2018 Mortality Risk Hinted for Laser Extraction of Device Leads
Medscape Medical News, March 23, 2018
ACC 2018 Fewer Events on Dabigatran After Post-Noncardiac Surgery MI
Medscape Medical News, March 23, 2018
ACC 2018 Cutting Antiplatelet Costs in ACS Improves Therapy, Not Outcomes
Medscape Medical News, March 23, 2018
ACC 2018 ANNEXA-4: Factor Xa Antidote Continues to Show Promise
Medscape Medical News, March 21, 2018
ACC 2018 Long-term Survival After HF Discharge Tied to Hospital Performance
Medscape Medical News, March 21, 2018
ACC 2018 SGLT-2 Inhibitors Tied to Less Death, HF, MI, Stroke: CVD REAL 2
Medscape Medical News, March 20, 2018
ACC 2018 Inflammatory Bowel Disease an Independent Risk Factor for MI
Medscape Medical News, March 19, 2018
ACC 2018 No Nitrite Exercise Boost in HF With Preserved EF: INDIE-HFpEF
Medscape Medical News, March 19, 2018
ACC 2018 His-Bundle vs RV Pacing for Bradycardia May Cut HF Event Risk
Medscape Medical News, March 16, 2018
ACC 2018 COMPASS: Prognosis 'Dire' in PAD With Major Limb Events
Medscape Medical News, March 16, 2018
ACC 2018 Chipping Away at Chemotherapy-Induced Cardiotoxicity
Medscape Medical News, March 15, 2018
ACC 2018 Canagliflozin May Have Most Benefit in Diabetes With HF: CANVAS
Medscape Medical News, March 15, 2018
ACC 2018 Shortening Dual Antiplatelet Therapy Ups MI Risk in ACS
Medscape Medical News, March 14, 2018
ACC 2018 CANTOS: Canakinumab Fails to Prevent New-Onset Diabetes
Medscape Medical News, March 14, 2018

ACC 2018 CARES Hints Mortality Risk in CV Patients on Gout Med Febuxostat
Medscape Medical News, March 13, 2018
ACC 2018 MOMENTUM 3: HeartMate 3 Improves Stroke-Free Survival at 2 Years
Medscape Medical News, March 13, 2018
ACC 2018 TRIUMPH: Triple Low-Dose Combo Pill a Success in Hypertension
Medscape Medical News, March 13, 2018
ACC 2018 Barbershop-Based Healthcare Cuts Hypertension in Blacks
Medscape Medical News, March 12, 2018
ACC 2018 Music Boosts Exercise Capacity During Cardiac Stress Test
Medscape Medical News, March 12, 2018
ACC 2018 New Studies Encourage Clopidogrel Genotyping
Medscape Medical News, March 12, 2018
ACC 2018 SECURE-PCI: 'Statin Loading' in ACS Doesn't Cut 30-Day Event Risk
Medscape Medical News, March 12, 2018
ACC 2018 TREAT: Ticagrelor Safe in STEMI Patients After Fibrinolysis
Medscape Medical News, March 11, 2018
ACC 2018 mSTOPS: Wearable Patch ECG Detects More AF Than Routine Care
Medscape Medical News, March 11, 2018
ACC 2018 COMBO Stent Impresses at 1 Year in 'All-Comers' Registry
Medscape Medical News, March 11, 2018
ACC 2018 ODYSSEY: Alirocumab Cuts CV Events, All-Cause Death Post-ACS
Medscape Medical News, March 10, 2018
ACC 2018 VEST: No Sudden Death Benefit Early Post-MI From LifeVest
Medscape Medical News, March 10, 2018
ACC 2018 Outdoor Temperature Swings Tied to STEMI Uptick
Medscape Medical News, March 9, 2018
ACC 2018 Flu Shot Cuts Risk for Death by Half in Heart Failure
Medscape Medical News, March 9, 2018
ACC 2018 Aspirin Linked to Lower Mortality in Diabetes With Heart Failure
Medscape Medical News, March 9, 2018
ACC 2018 Trials Headlining ACC Session 'Promise to Be Practice Changing'
Medscape Medical News, March 6, 2018

Popular News from ACC 2017

Evolocumab Added to Statins Cuts CV Events in FOURIER Trial UPDATED // In the heavily anticipated FOURIER outcomes trial, the PCSK9 inhibitor met its primary and key secondary measures. But is it enough to shut down concerns over costs for the medication class?
Medscape Medical News, Mar 17, 2017
SURTAVI: TAVR, SAVR Stand Toe-to-Toe in Intermediate-Risk Patients UPDATED // While SURTAVI dashed hopes for a superiority claim, its findings support the ongoing drift of transcatheter aortic-valve replacement to lower-risk patients.
Medscape Medical News, Mar 17, 2017
SPIRE Trials: Immune Response Thwarts PCSK9 Inhibitor Bococizumab In the trials, which were halted early, a immune response in many patients diminished the drug's potent LDL-lowering effects. In another analysis, immunogenicity was much less of an issue for alirocumab.
Medscape Medical News, Mar 17, 2017

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Perspectives From ACC

Cardio-oncology Not Just for Subspecialists
Melissa K. Walton-Shirley, MD; Ana Barac, MD, PhD; Laxmi S. Mehta, MD
Iron Therapy Improves HF, But Not by Improving Anemia
Ileana Piña, MD, MPH; Darlington O. Okonko, MBBS, MRCP, PhD
Nebulized Nitrite for HFpEF? Don't Hold Your Breath
Interviewer: Ileana L. Piña, MD, MPH; Interviewee: Barry A. Borlaug, MD
Will ODYSSEY Clear Hurdles for PCSK9 Inhibitor Access?
Seth J. Baum, MD; Matthew J. Budoff, MD
His Bundle Pacing 'Very Viable' Alternative to RV Pacing
John M. Mandrola, MD; Gopi Dandamudi. MD; Pugazhendhi Vijayaraman, MD
Women's Hearts: How Women Can Walk Away From Heart Failure
JoAnn E. Manson, MD, DrPH
Sanjay Kaul Grades Four Big Trials From ACC 2018
Sanjay Kaul, MD
More Positives for PCSK9 inhibitors and the LDL-C Hypothesis
Interviewer: John M. Mandrola MD Interviewee: Gregory G. Schwartz, MD, PhD

Bloggers From The Floor

Pharmacists and Barbers on the Cutting Edge of Medicine Dr Mandrola's hands-down favorite study from the 2018 American College of Cardiology meeting showed that a pharmacist-led intervention in black-owned barbershops cut hypertension in black men.
Ten Quick Thoughts on ODYSSEY Despite a suggested mortality benefit for the PCSK9 inhibitor alirocumab, in high-risk ACS patients, a return to lipid targets may be the cost-effective lesson from this trial, argues Dr Mandrola.
The VEST Trial Failed, and So Did the Press Release The first randomized trial on the wearable cardioverter defibrillator didn't meet its primary endpoint, yet the press release was overly positive.
MOMENTUM-3: The Future of the LVAD Is Here and Now A trial showing better outcomes for HeartMate 3 over HeartMate II sends Dr Walton-Shirley down memory lane to recall the patients she has referred for implantation of a left ventricular assist device (LVAD).
Another Way to Save a Life: the MANAGE Trial Dr Walton-Shirley was impressed by a study on dabigatran for myocardial injury after noncardiac surgery at the American College of Cardiology Annual Scientific Session.
How Want Became Need With ODYSSEY Dr Walton-Shirley would like to prescribe more PCSK9 inhibitors, given positive data from the American College of Cardiology meeting, but the prior authorization process may break her first

Pre-Meeting Perspective

Mandrola Previews 2018 ACC
John Mandrola, MD

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