Successful Liver Transplantation in Patients With Active SARS-CoV-2 Infection

Charles A. Mouch; Sophoclis P. Alexopoulos; Richard W. LaRue; Hannah P. Kim


American Journal of Transplantation. 2022;22(11):2694-2696. 

In This Article

Abstract and Introduction


The Coronavirus Disease 2019 (COVID-19) pandemic has substantially impacted solid organ transplantation, including temporary inactivation of waitlist candidates with COVID-19 infection. We report two cases of liver transplantation (LT) in individuals with asymptomatic COVID-19 infection. The first patient is a 68-year-old female with decompensated cirrhosis complicated by worsening frailty and sarcopenia. The second patient is a 22-year-old female with acute liver failure likely secondary to drug/toxin exposure. Both patients were treated with COVID-19-directed therapies and neither patient developed symptomatic disease. These cases demonstrate that LT can be safely performed in select patients with asymptomatic COVID-19 infection at the time of transplant.