In conclusion, axSpA patients had a widespread distribution of BME with high volumes, whereas BME in the MBP group predominantly were located in the middle anterior part of the sacrum, demonstrating a 'strain-related' BME pattern. Furthermore, BME in the ligamentous compartment was almost exclusively seen in axSpA, which also demonstrated a widespread distribution of structural changes. In the early diagnostic period, these findings may contribute to the distinction between axSpA and MBP patients with SIJ MRI changes and thereby facilitate the axSpA diagnosis.
ASAS: Assessment of SpondyloArthritis International Society; axSpA: Axial spondyloarthritis; BME: Bone marrow edema; FMD: Fatty marrow deposition; ICC: Intraclass correlation; MBP: Mechanical back pain; OR: Odds ratios; SIJ: Sacroiliac joint; SpA: Spondyloarthritis; STIR: Short tau inversion recovery.
There were no grants or other financial supporters supporting the study. Availability of data and materials
All data generated and analysed during this study are included in this published article. The datasets used and analysed during the current study are available from the corresponding author on reasonable request.
Ethics approval and consent to participate
The study was approved by the Regional Scientific Ethics Committee for Southern Denmark and the Danish Data Protection Agency and was conducted in accordance with the Declaration of Helsinki II and subsequent revisions. Institutional Review Board approval was granted.
Consent for publication
Before inclusion, patients gave written consent for the publication of their de-identified data.
Arthritis Res Ther. 2022;24(75) © 2022 BioMed Central, Ltd.
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