Multisystem Inflammatory Syndrome in Adults

A Case Report and Review of the Literature

Fardad Behzadi; Nicolas A. Ulloa; Mauricio Danckers


J Med Case Reports. 2022;16(102) 

In This Article


The current coronavirus disease (COVID-19) pandemic has brought the recognition of multisystem inflammatory syndrome in adults (MIS-A) as a de novo entity temporally associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral infection in adults. Hypothesis about its true pathophysiology remains controversial. Its initial presentation, response to empiric therapy, and clinical outcomes are widely variable. We report the case of a 22-year-old female who presented with distributive shock after 3 days of fever, sore throat, and right-sided neck pain. She was diagnosed with MIS-A and successfully treated. We further provided the reader with an in-depth review of the current published case report of MIS-A available in the medical literature, and review the pathophysiology and clinical resemblance and difference to Kawasaki disease.