Female Adult Acne and Androgen Excess

A Report From the Multidisciplinary Androgen Excess and PCOS Committee

Enrico Carmina; Brigitte Dreno; W. Anne Lucky; W. George Agak; Anuja Dokras; Jin Ju Kim; Rogerio A. Lobo; Fahimeh Ramezani Tehrani; Daniel Dumesic


J Endo Soc. 2022;6(3) 

In This Article


AE-PCOS Society Task force

The AE-PCOS Society Board appointed an expert task force from pertinent medical disciplines (dermatology, endocrinology, reproductive endocrinology) to determine the current state of knowledge concerning adult female acne and its relationship to androgen excess, and to provide evidence-based recommendations that could be valid for all specialists taking care of this disorder. Members of the Task force were selected from those researchers who had authored many original articles in the field. All members of the task force declared no conflicts of interest or financial interests that might interfere with their objectivity and collaborative effort.


Each section of this review was prepared by at least 2 investigators and then reviewed by all members of the task force. Analyzed papers included individual studies, systematic reviews, and abstracts published in the English scientific literature. Peer-reviewed studies evaluating adult acne vulgaris (acne) published through 2020 were reviewed. Criteria for inclusion/exclusion of the published papers relating to each section were agreed upon by at least 2 reviewers in each area and arbitrated by a third when necessary. Levels of evidence of the were assessed and graded from A to D.[7,8] Levels of evidence A or B were needed for recommendations regarding diagnosis and therapy of female adult acne.

The final manuscript was reviewed and approved by the AE-PCOS Society Board of Directors. Institutional Review Board approval was not obtained because the study reviewed publicly available medical literature.