Materials and Methods
In this preliminary case series, patients with difficult-to-heal skin lesions were treated with a synthetic hybrid-scale fiber matrix (Restrata; Acera Surgical, Inc). In all cases, multiple applications of the synthetic matrix were used based on clinician discretion. Until sufficient healing was observed, the matrix was used in conjunction with negative pressure wound therapy (NPWT) (ABTHERA ADVANCE Open Abdomen Dressing, V.A.C. Therapy Unit, V.A.C. VERAFLO Therapy, and V.A.C. ULTA Therapy System [3M]) for the treatment of cutaneous wounds and was set to –100 mm Hg. The instillation fluid used was Vashe Wound Solution (Urgo Medical).
Each case was observed throughout the healing process, and representative photographs of the wounds were taken over the course of healing. Data were collected retrospectively by reviewing medical records. The study was exempt from institutional review board approval because of the absence of patient identifying information, the limited number of patients (n = 3), and the insignificant risk of a retrospective study.
Wounds. 2021;33(9):237-244. © 2021 HMP Communications, LLC