Is Anxiety a Risk Factor for Hypertension?

Pavankumar Kamat

Disclosures

September 16, 2021

Takeaway

  • A meta-analysis found anxiety to be associated with an increased risk of hypertension, which persisted even after adjustment for possible confounders.

Why this matters

  • Findings emphasise the importance of and opportunities to treat both hypertension and anxiety concurrently.

Study design

  • Researchers at the University of Southampton conducted a meta-analysis of 59 studies (n=4,012,775), identified through a literature search across PubMed and Ovid and PsycINFO databases.

  • Funding: None.

Key results

  • Anxiety was associated with an increased risk of hypertension in cross-sectional studies (OR, 1.37; 95% CI, 1.21-1.54; I2, 98.17%) and in prospective studies (OR, 1.40; 95% CI, 1.23-1.59; I2, 90.26%).

  • After adjusting for confounders, the risk of hypertension remained significant in cross-sectional studies (OR, 1.35; 95% CI, 1.08-1.69; I2, 99.12%) as well as in prospective studies (OR, 1.37; 95% CI, 1.19-1.57; I2, 90.28%).

Limitations

  • Heterogeneity among studies.

  • Results may have limited generalisability.

 

Lim LF, Solmi M, Cortese S. Association between Anxiety and Hypertension in Adults: A Systematic Review and Meta-Analysis. Neurosci Biobehav Rev. 2021 Sep 02 [Epub ahead of print]. doi: 10.1016/j.neubiorev.2021.08.031. PMID: 34481847.  View abstract 

This clinical summary originally appeared on Univadis, part of the Medscape Professional Network.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....