The Changing Face of Trigeminal Neuralgia

A Narrative Review

Stine Maarbjerg MD, PhD; Rafael Benoliel BDS (Hons)


Headache. 2021;61(6):817-837. 

In This Article

Trigeminal Neuralgia Epidemiology

Lifetime prevalence figures suggest around 70 TN cases per 100,000 population, and it is, therefore, a rare condition.[8] Recent data suggest an incidence of 12.6–27/100,000 patient-years.[9] The crude annual incidence of TN is 4.3–8 per 100,000; higher in females (5.7) than in males (2.5). However, in those >80-years-old, males have a very high incidence of 45/100,000.[8,10] Peak incidence begins at 50–60 years and increases with age; in 60- to 69-year-olds, it is 17.5/100,000, whereas in >80-year-olds, it is 25.9/100,000.[11]