A Systematic Review and Meta-Analysis to Inform Cancer Screening Guidelines in Idiopathic Inflammatory Myopathies

Alexander G. S. Oldroyd; Andrew B. Allard; Jeffrey P. Callen; Hector Chinoy; Lorinda Chung; David Fiorentino; Michael D. George; Patrick Gordon; Kate Kolstad; Drew J. B. Kurtzman; Pedro M. Machado; Neil J. McHugh; Anna Postolova; Albert Selva-O'Callaghan; Jens Schmidt; Sarah Tansley; Ruth Ann Vleugels; Victoria P. Werth; Rohit Aggarwal


Rheumatology. 2021;60(6):2615-2628. 

In This Article


This meta-analysis has quantified the risk of cancer associated with a large number of clinical risk factors and MSAs, which can inform cancer screening practices for IIM patients. In addition, the systematic review of available evidence related to utility of cancer screening investigations, although limited, can also inform clinical decisions and aid guideline development in this area. Overall, these results can inform the development of cancer screening guidelines, thus potentially leading to earlier cancer diagnosis and improved patient outcomes.