Biologic Treatment Algorithms for Moderate-to-Severe Psoriasis With Comorbid Conditions and Special Populations

A Review


Am J Clin Dermatol. 2021;22(4):425-442. 

In This Article

Approach to the Evidence

Our review objective was to create evidence-based treatment algorithms derived from existing literature. We provide biologic treatment algorithms for moderate-to-severe psoriasis in patients with comorbidities and in special populations. Treatment algorithms are organized as follows:

  • Medications within a biologic class and with similar efficacy and safety profiles are separated by commas.

  • If all of the drugs of a class are assigned equal weight, the class is listed (e.g., IL-17 inhibitors) in place of individual biologic agents.