Conclusion
SCH participants who were at an intermediate-to-high risk of developing CAD (AR10y) were significantly more likely to exhibit region-specific CV fat tissue (TAT) and noninvasive visceral adipose indices (CVAI and BRI) than EU individuals, especially in Taiwanese women. These findings suggest that mild thyroid failure also independently contributes to the development of abnormal fatty distribution.
Abbreviations
ABSI, a body shape index; AR10y, absolute risk of cardiovascular event in 10 years; BMI, body mass index; BRI, body roundness index; CV, cardiovascular; CVAI, Chinese visceral adiposity index; CVD, cardiovascular disease; DM, diabetes mellitus; EAT, epicardial adipose tissue; EU, euthyroid; FRS, Framingham risk score; FT4, free thyroxine; HDL-C, high-density lipoprotein cholesterol; HTN, hypertension; LDL-C, low-density lipoprotein cholesterol; MDCT, multidetector computed tomography; Mets, metabolic syndrome; OR, odds ratio; PCF, pericardial fat; SBP, systolic blood pressure; SCH, subclinical hypothyroidism; TAT, thoracic periaortic fat; TG, triglycerides; TSH, thyrotropin; VAT, visceral adipose tissue; WC, waist circumference.
Additional Information
Data Availability
The data used in this study are available from the corresponding author on reasonable request.
J Endo Soc. 2021;5(6) © 2021 Endocrine Society