Applications and Future Directions for Optical Coherence Tomography in Dermatology

B. Wan; C. Ganier; X. Du-Harpur; N. Harun; F.M. Watt; R. Patalay; M.D. Lynch


The British Journal of Dermatology. 2021;184(6):1014-1022. 

In This Article

Optical Coherence Tomography in Normal Skin

Earlier studies investigated the correlation of OCT findings with histopathological appearances.[25–28] Angiographic OCT studies of normal skin have revealed characteristic differences in the structure of the vasculature according to body site. This reflects both differences in the thickness of the epidermis and intrinsic differences in the morphology of blood vessels at different anatomical sites.[14,29] Polarization-sensitive OCT detects layered, well-organized collagen in normal skin and disordered organization of collagen fibres in the dermis, which can result from pathology such as burns[30] and basal cell cancer.[31,32]