Rising Significance of Antibiotic Stewardship in Urology and Urinary Tract Infections

A Rapid Review

Laila Schneidewind; Jennifer Kranz; Zafer Tandogdu


Curr Opin Urol. 2021;31(4):285-290. 

In This Article


Our review has identified that inappropriate use of antibiotics in UTIs remains as a pertinent issue. One of the most striking areas was the overuse of fluoroquinolones in asymptomatic bacteriuria. Studies indicate that ABS interventions can improve patient care and outcomes as well as reduce multidrug-resistant pathogens. Consequently, expanding on areas for ABS interventions can be beneficial for patients. For instance, involvement of pharmacists, improvement of guideline adherence, and guidelines themselves were some of the intervention areas noted. Such ABS interventions would differ according to jurisdictions and hospitals. Another key area that contributes to ABS is improved selection of empirical antibiotics that can achieved with locally applicable infection surveillance data. The Global Prevalence Study of Infections in Urology surveillance is to our knowledge the only study that has a sequential measure of different UTIs in urology departments using validated conditions, so we strongly advise urologists to participate in this study.

Unfortunately, most of the published studies from the past 18 months are retrospective. Higher quality data are necessary in areas for new targets for ABS intervention. Finally, we hope that results from the ongoing 43 registered trials about ABS in UTI will be available soon.