Sleep disorders were significantly associated with an increased risk of osteoarthritis (OA).
The association was significant across all sex, age and OA type subgroups, with the exception of patients aged >80 years and those with knee OA.
Why this matters
Findings highlight the importance of improving the diagnosis and management of sleep disorders to mitigate their potentially deleterious effects on OA.
This case-control study included patients (age, ≥18 years) with a diagnosis of OA across 256 UK general practices (1997-2016).
175,966 patients with OA were matched (1:1) with participants without OA.
Funding: None disclosed.
Sleep disorders had a positive and significant association with an increased risk of OA (OR, 1.25; 95% CI, 1.22-1.29; P<.001).
This association was substantiated in all sex and age subgroups, except in patients aged >80 years (OR, 0.94; 95% CI, 0.88-1.01; P=.069), ORs decreasing with increasing age.
In terms of the type of sleep disorder, the risk of developing OA significantly increased with (OR; 95% CI):
non-organic sleep disorders (1.51; 1.44-1.58; P<.001);
hypersomnia (1.79; 1.44-2.22; P<.001); and
sleep apnoea (3.79; 3.20-4.50; P<.001).
The association between sleep disorders and OA was significant in all OA subgroups, except in patients with knee OA (OR, 0.97; 95% CI, 0.86-1.10; P=.613).
Study did not include all sleep disorders (e.g., unspecified sleep disorder).
This clinical summary originally appeared on Univadis, part of the Medscape Professional Network.
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Cite this: Pavankumar Kamat. Sleep Disorders Linked to an Increased Risk of Osteoarthritis - Medscape - May 06, 2021.