Prevalence of Thrombotic Complications in ICU-Treated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning

Saeed Mirsadraee, MD, PhD, FRCR, FRCPE; Diana A. Gorog, MD, PhD, FRCP; Ciara F. Mahon, BCh, BAO, MSc, MRCP; Bhavin Rawal, MBBS, FRCR; Thomas R. Semple, FRCR; Edward D. Nicol, MD, FRCP, FRCR; Deepa R. J. Arachchillage, MD, MRCP, FRCPath; Anand Devaraj, MD, FRCR; Susanna Price, PhD, FRCP; Sujal R. Desai, MD, FRCR, FRCP; Carole A. Ridge, FFRRCSI; Suveer Singh, MD, PHD; Simon P. G. Padley, MBBS, FRCR


Crit Care Med. 2021;49(5):804-815. 

In This Article


Among COVID-19 patients needing ventilatory support on ICU, arterial and venous thrombosis was observed in nearly three in five patients. Thromboses were related to adverse outcome, and importantly the presence of these thromboses was not predicted based on usual biomarkers of coagulation at admission to ICU. Since many thrombotic complications are clinically silent, we propose that systematic CT imaging should be considered in all ICU-treated COVID-19 patients and may improve patient outcome if implemented early and routinely.