Bariatric Surgery May Improve Lower Urinary Tract Symptoms in Men with Obesity

Sarfaroj Khan 

Disclosures

April 16, 2021

Takeaway

  • Bariatric surgery demonstrated a significant improvement of lower urinary tract symptoms (LUTS) in men with obesity.

  • Additionally, a reduction in body mass index (BMI) and mean total body weight (TBW) was observed.

Why this matters

  • Findings warrant future studies to investigate the detailed pathophysiological mechanisms underlying the development of LUTS in male patients with obesity and their improvement following weight loss surgery.

Study design

  • UK researchers performed a meta-analysis of 7 studies including 334 male patients who underwent bariatric surgery.

  • Primary outcome: LUTS before and after bariatric surgery assessed using the International Prostate Symptom Score (IPSS).

  • Secondary outcomes: changes in BMI and mean TBW.

  • Funding: None disclosed.

Key results

  • IPSS score varied from 3-12.7 pre-operatively and 1.9-6.9 post-operatively.

  • Bariatric surgery was associated with a significant improvement in the IPSS score (mean difference [MD], 2.82; 95% CI, 0.96-4.69; I2, 89%; P=.003).

  • Bariatric surgery was associated with a significant reduction in BMI (MD, 9.41; 95% CI, 7.67-11.15; I2, 58%; P<.00001) and mean TBW (MD, 28.33; 95% CI, 21.10-35.57; I2, 54%; P<.00001).

Limitations

  • Heterogeneity among studies.

  • Results may have limited generalisability.

 

Stefanova I, Currie AC, Newton RC, Albon L, Slater G, Birnie A, Hawkins W, Pring C. Systematic Review and Meta-Analysis of the Impact of Bariatric Surgery on Lower Urinary Tract Symptoms in Males. Obes Surg. 2021 Apr 13 [Epub ahead of print]. doi: 10.1007/s11695-021-05403-z. PMID: 33847876.  View abstract 

This clinical summary originally appeared on Univadis, part of the Medscape Professional Network.

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