Bariatric surgery demonstrated a significant improvement of lower urinary tract symptoms (LUTS) in men with obesity.
Additionally, a reduction in body mass index (BMI) and mean total body weight (TBW) was observed.
Why this matters
Findings warrant future studies to investigate the detailed pathophysiological mechanisms underlying the development of LUTS in male patients with obesity and their improvement following weight loss surgery.
UK researchers performed a meta-analysis of 7 studies including 334 male patients who underwent bariatric surgery.
Primary outcome: LUTS before and after bariatric surgery assessed using the International Prostate Symptom Score (IPSS).
Secondary outcomes: changes in BMI and mean TBW.
Funding: None disclosed.
IPSS score varied from 3-12.7 pre-operatively and 1.9-6.9 post-operatively.
Bariatric surgery was associated with a significant improvement in the IPSS score (mean difference [MD], 2.82; 95% CI, 0.96-4.69; I2, 89%; P=.003).
Bariatric surgery was associated with a significant reduction in BMI (MD, 9.41; 95% CI, 7.67-11.15; I2, 58%; P<.00001) and mean TBW (MD, 28.33; 95% CI, 21.10-35.57; I2, 54%; P<.00001).
Heterogeneity among studies.
Results may have limited generalisability.
This clinical summary originally appeared on Univadis, part of the Medscape Professional Network.
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Cite this: Sarfaroj Khan. Bariatric Surgery May Improve Lower Urinary Tract Symptoms in Men with Obesity - Medscape - Apr 16, 2021.