NICE advises that paracetamol and/or topical non-steroidal anti-inflammatory drugs (NSAIDs) should be considered ahead of oral NSAIDs, COX-2 inhibitors or opioids. Where paracetamol or topical NSAIDs provide insufficient pain relief then the addition of an oral NSAID/COX-2 inhibitor to paracetamol should be considered for people with osteoarthritis.
Topical capsaicin should be considered as an adjunct to core treatments for knee or hand osteoarthritis, but rubefacients should not be used for treating osteoarthritis. Intra-articular corticosteroid injections, but not intra-articular hyaluronan injections, should be considered as an adjunct to core treatments for the relief of moderate to severe pain in people with osteoarthritis.
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Cite this: Dr Rob Hicks. Quiz: Test Your Knowledge of Osteoarthritis Guidelines - Medscape - Mar 23, 2021.