Outcomes of Upper Gastrointestinal Bleeding Are Similar Between Direct Oral Anticoagulants and Vitamin K Antagonists

Claire Gouriou; Guillaume Bouguen; Pierre Lahmek; Agnes Pelaquier; Ramuntxo Arotcarena; Armand Garioud; Stephanie De Montigny-Lenhardt; Arnaud Pauwels; David Zanditenas; Claire Charpignon; Remi Combes; Stephane Nahon; Vincent Quentin


Aliment Pharmacol Ther. 2021;53(6):688-695. 

In This Article


DOACs do not alter outcomes of UGIB as compared to VKA. Comorbidities and associated treatment seem to be the most important factors worsening prognosis of UGIB. Further studies are needed to evaluate each DOAC specifically and the preciserole of beta-blockers.