Does a Combined Intravenous-volatile Anesthesia Offer Advantages Compared to an Intravenous or Volatile Anesthesia Alone

A Systematic Review and Meta-analysis


BMC Anesthesiol. 2021;21(52) 

In This Article


CIVA showed a similar risk for PONV in the recovery room compared to a TIVA and in the early postoperative period a reduced risk compared to a BAL. However, this effect was not consistent for the first 24 postoperative hours with no difference between CIVA and BAL. The CIVA showed lower rates of intraoperative movements compared to a TIVA with the major limitation of only two studies providing data. These results must be seen in the context of moderate to low study quality with significant heterogeneity. We suggest carrying out a sufficiently powered multi-center randomized controlled trial to evaluate reasonable benefits for a combination of propofol and volatile anesthetics.