Oral Mosapride Can Provide Additional Antiemetic Efficacy Following Total Joint Arthroplasty Under General Anesthesia

A Randomized, Double-blinded Clinical Trial

Jinwei Xie; Yingchun Cai; Jun Ma; Qiang Huang; Fuxing Pei


BMC Anesthesiol. 2020;20(297) 

In This Article


Prophylactic use of concurrent dexamethasone and oral mosapride can reduce overall incidence and severity of PONV, especially postoperative nausea, as well as increase complete response rates during the first 12 h after total hip and knee arthroplasty when compared with other patients. While it seemed that oral mosapride would not provide additional effect on reducing the rate of severe PONV when compared with dexamethasone alone. Preemptive oral mosapride can also improve postoperative appetite and bowel function.