Deep Sedation Using Propofol Target-controlled Infusion for Gastrointestinal Endoscopic Procedures

A Retrospective Cohort Study

María E. García Guzzo; María S. Fernandez; Delfina Sanchez Novas; Sandra S. Salgado; Sergio A. Terrasa; Gonzalo Domenech; Carlos A. Teijido


BMC Anesthesiol. 2020;20(195) 

In This Article


Patients undergoing GIEPs under propofol TCI sedation combined with fentanyl were not exempted from experiencing cardiovascular or respiratory unplanned events, specifically grade II and III obese patients who showed a significant dose-effect relationship with SpO2 < 90% events. Nonetheless, it appears to be an effective sedative strategy for GIEPs with the benefits of acceptable rates of unplanned adverse events, short discharge times, and rapid patient turnover. Further prospective studies should be conducted to accurately assess patient comfort and quality of sedation for this type of procedure.