Patients undergoing GIEPs under propofol TCI sedation combined with fentanyl were not exempted from experiencing cardiovascular or respiratory unplanned events, specifically grade II and III obese patients who showed a significant dose-effect relationship with SpO2 < 90% events. Nonetheless, it appears to be an effective sedative strategy for GIEPs with the benefits of acceptable rates of unplanned adverse events, short discharge times, and rapid patient turnover. Further prospective studies should be conducted to accurately assess patient comfort and quality of sedation for this type of procedure.
ACLS: Advanced cardiac life support; ASA: American Society of Anesthesiologists; BMI: Body mass index; EGD: Esophagogastroduodenoscopy; ESA: European Society of Anesthesiology; GIEP: Gastrointestinal endoscopic procedure; HR: Heart rate; OR: Operating room; PACU: Post anaesthetic care unit; PONV: Post-operative nausea and/or vomiting; SBP: Systolic blood pressure; SGD: Supraglottic device; TCI: Target-controlled infusion
Availability of data and materials
The datasets used and/or analysed during the current study available from the corresponding author on reasonable request.
Ethics approval and consent to participate
Ethical approval was provided by the Ethics Committee of the Hospital Italiano de Buenos Aires, Buenos Aires, Argentina (Chairperson: Dr. Augusto Pérez, Ethical Committee N° 3885) on September 24, 2018. The requirement for written informed consent was waived due to the retrospective nature of the study.
Consent for publication
BMC Anesthesiol. 2020;20(195) © 2020 BioMed Central, Ltd.