Brief Review of Chloroquine and Hydroxychloroquine Toxicity and Management

Jacob A. Lebin, MD; Kathy T. LeSaint, MD

Disclosures

Western J Emerg Med. 2020;21(4):760-763. 

In This Article

Summary

Poisoning from CQ or HCQ can be life-threatening and may become more frequent with increased media attention and use during the COVID-19 pandemic. Acute toxicity is characterized by direct cardiotoxicity, hypokalemia, and precipitous cardiovascular collapse. Treatment includes aggressive gastrointestinal decontamination, sodium bicarbonate for QRS interval widening, and high-dose diazepam and epinephrine in patients with severe toxicity and evidence of shock.

Comments

3090D553-9492-4563-8681-AD288FA52ACE

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