Transition of Patients to and From Insulin Degludec

A Clinical Challenge

Irl B. Hirsch; Boris Draznin


J Clin Endocrinol Metab. 2020;105(6) 

In This Article


We present 5 clinical scenarios where the patients were transitioned to or from insulin degludec. Because there are no data and no current consensus, we have polled 200 diabetes care providers soliciting their opinion as to how they would handle these clinical situations.

We received 30 detailed responses (15%). Even though all answers, summarized after each case, might be reasonable, and there might not be a single correct answer, we wish to express our opinion that is based on PK and PD of these insulins.