Antiarrhythmic Treatment in Atrial Fibrillation

Seema Ledan, PharmD


US Pharmacist. 2020;45(2):24-27. 

In This Article

Role of Pharmacists

Pharmacists may play a vital role in the management of AF patients taking antiarrhythmics. Discussing adverse events and administration requirements, reviewing drug interactions, and recommending monitoring parameters are just a few of the key responsibilities. A retrospective chart review was conducted to show the impact of a pharmacy-based outpatient clinic for patients receiving antiarrhythmic medications.[15] The research showed that pharmacist monitoring increased patient adherence to required monitoring/testing parameters postdischarge, detected unrecognized adverse events such as pulmonary function decline, QT prolongation, and lab abnormalities in 38% of visits, and identified clinically significant drug interactions. A similar retrospective cohort study with a pharmacy-cardiology collaborative program was conducted to assess antiarrhythmic management and also concluded significantly more clinical interventions (P <.01) in the postintervention program due to dose adjustments or discontinuation, monitoring requirements, and electrolyte supplementation.[16]