Orolabial Lymphogranuloma Venereum, Michigan, USA

Sahrish Ilyas; Deborah Richmond; Gerald Burns; Katherine E. Bowden; Kimberly Workowski; Ellen N. Kersh; Pranatharthi H. Chandrasekar


Emerging Infectious Diseases. 2019;25(11):2112-2114. 

In This Article

Abstract and Introduction


Orolabial lymphogranuloma venereum was diagnosed for a man in Michigan, USA, who had sex with men, some infected with HIV. High index of suspicion for lymphogranuloma venereum led to accurate diagnosis, successful therapy, and description of an L2b variant with a unique genetic mutation.


Lymphogranuloma venereum (LGV) is typically a genital ulcer disease with inguinal adenopathy, caused by L serovars of Chlamydia trachomatis. Most commonly today, the infection causes proctocolitis, particularly in men who have sex with men (MSM) with HIV infection. We describe a case of LGV at an unusual site (orolabial) with submandibular adenopathy in a man with a history of having sex with men with advanced HIV infection.