Necrotizing Myositis: A Rare Necrotizing Soft Tissue Infection Involving Muscle

A Rare Necrotizing Soft Tissue Infection Involving Muscle

Harika Boinpally, MD; Raelina S. Howell, MD; Bebu Ram, MD; Virginia Donovan, MD; Michael Castellano, MD; Jon S. Woods, MD; Scott Gorenstein, MD, FACEP


Wounds. 2018;30(12):E116-E120. 

In This Article


Necrotizing soft tissue infections, particularly NM, are associated with high morbidity and mortality rates; therefore, a high index of suspicion is required for early diagnosis. The most common causative organisms are GABHS and C perfringens; however, rare organisms like S intermedius, C clostridioforme, and Peptostreptococcus also can lead to aggressive NM. Patients presenting with NM can be managed by a dedicated wound care team. Treatment includes prompt surgical intervention and broad-spectrum antibiotics. Surgical intervention within 24 hours significantly increases survival, emphasizing the importance of rapid diagnosis and expeditious treatment.