Developments in the Treatment of Benign Essential Blepharospasm

Michael T. Yen


Curr Opin Ophthalmol. 2018;29(5):440-444. 

In This Article


There is currently no cure for essential blepharospasm. Nevertheless, there are a number of medical treatment options which can be attempted to alleviate the significant functional disability in patients affected with this disorder. All patients should be referred to their local patient support group. Botulinum toxin injections to control the motor signs should be the first-line treatment for almost all patients. Photochromatic modulation can be beneficial in improving the sensory symptoms of photophobia. Oral pharmacotherapy should be considered an adjunct therapy. Surgical myectomy can be used for patients who continue to have blepharospasm and/or apraxia of lid opening despite maximal medical therapy.