New Approaches in Managing Interstitial Cystitis/Bladder Pain Syndrome

Amber Jerauld, PharmD, BCACP; Lyndsay Wormuth, PharmD, BCACP; Brent Carlson, PharmD, BCPS, BCCCP


US Pharmacist. 2016;41(9):29-33. 

In This Article


Diagnosis consists of collecting the patient's history of symptoms and associated conditions, physical examination, and urine testing. Cystoscopy may be used to exclude other etiologies but is not required to make the diagnosis of IC/BPS. It may be used to identify or rule out other conditions and should be performed if patients are experiencing hematuria. Cystoscopy can also identify structural lesions or an intravesical foreign body, helping to identify a small subset of patients that would benefit from cystoscopic treatment.[3,7]

Validated symptom scales have been developed to assess IC/BPS severity and clinical progress, but they do not help distinguish IC/BPS from other conditions. There have been several scales used, including the IC Symptom and Problem Index, the Genitourinary Pain Index, and the Pelvic Pain and Urgency/Frequency (PUF) questionnaire.[1,3,9]

Infection and hematuria should be excluded, so urinalysis with microscopy should be performed on all patients with suspected IC/BPS. A postvoid residual urine volume should also be measured.[3]