Procalcitonin levels are elevated after pediatric cardiac surgery reaching a maximum on POD1. Levels of procalcitonin at admission to PICU correlated to duration of CPB, aortic cross-clamp time, and initial serum lactate and were significantly higher in children suffering a MAE. Furthermore, markers of postoperative morbidity (LOS in PICU, length of inotropic, and respiratory support) correlated with procalcitonin levels at admission. Patients with clinical suspicion of infection-associated deterioration in the later postoperative course already had significantly higher procalcitonin levels at admission to PICU.
We thank Florian Zeman, biostatistician (Center for Clinical Studies, University Hospital Regensburg, Germany) for the statistical support.
Pediatr Crit Care Med. 2016;17(7):624-629. © 2016 Lippincott Williams & Wilkins