Diagnosis of Allergic Bronchopulmonary Aspergillosis: A Case-Based Approach

Sahajal Dhooria; Ritesh Agarwal


Future Microbiol. 2014;9(10):1195-1208. 

In This Article

Should All Asthmatics Be Screened for ABPA?

All asthmatic patients should be screened for ABPA as clinical symptoms and signs lack sensitivity and specificity (Box 2). Moreover, many patients with ABPA, including those with bronchiectasis, surprisingly do not manifest with worsening asthma control. There is also considerable burden of the disease with an estimated 4.8 million patients globally.[20] The prevalence of ABPA complicating asthma in special clinics has been estimated to approximately 13%.[21] Importantly, early diagnosis and treatment of ABPA can prevent the development of bronchiectasis or halt its progression once it has already set in.[22] Also, the investigations used in screening have no adverse effects. These points underscore the need for routine screening of asthmatic patients for ABPA.