Molecular Profiling and Companion Diagnostics: Where is Personalized Medicine in Cancer Heading?

Mukesh Verma

Disclosures

Personalized Medicine. 2014;11(8):761-771. 

In This Article

Conclusion

Personalized medicine is the right intervention for the right patient at the right time. Remarkable progress has been made in the past decade in the field of personalized medicine in cancer, mainly because of the development of the advanced high-throughput 'omics' technologies. These approaches, especially genomics, are complementary to each other. Multiple markers based on molecular profiling provide better results than pathological analysis in diagnosing cancer. Remaining challenges in the field include approval of these technologies for clinical use and reimbursement of expenses by insurance companies. Developing new algorithms based on molecular imaging and making new risk prediction models are additional challenges in personalized medicine. It is also important to understand how to incentivize the development of CoDx tests and drugs. In addition, well-conducted, prospective validation studies are needed to improve existing personalized therapy.

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