NAFLD has captured the attention of physicians of different disciplines and is high among the causes of consulting medical practitioners around the world. In addition, NAFLD is a serious disease problem that clinicians need to deal with. Consequently, NAFLD challenges ordinary clinical practice and invites physicians to improve both conventional diagnostic procedures and therapeutic approaches. The knowledge of the human genome sequence and the availability of recent technologies to decipher individual patients' genetic make-up also invite a fully integrated genomic medicine. Nevertheless, integration of the 'omics' technologies and phenotypic data is still full of uncertainties. Hopefully, future research programs that integrate health records – ideally electronic ones – with patients' genomic, transcriptomic, proteomic and metabolomic information will change our ability to control or cure the disease eventually.
Personalized Medicine. 2014;11(8):735-743. © 2014 Future Medicine Ltd.