Limitations & Recommendations for Future Research
This study has several limitations. Although the sample size is relatively large for a qualitative study, it is still limited in size. Moreover, the participants were self-selected in that they all chose to participate in the research. Therefore, these participants may hold views that are different from individuals who would decline to participate in research and/or would not want genetic testing.
Published reports that have analyzed different themes from this research team include: Barlevy et al., who addressed reproductive decision-making in the context of genetic predispositions to sudden cardiac death ; Cohen et al., who discussed special considerations for genetic testing with adolescents ; Erskine et al., who described the advantages of an interdisciplinary approach to personalized medicine ; Linder et al., who identified major concerns associated with an implantable cardioverter-defibrillator (ICD) ; and Erskine et al., who analyzed motivations to pursue genetic testing in individuals with a personal or family history of cardiac events or sudden cardiac death . The entire data set is available from the corresponding author.
The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung, and Blood Institute or the NIH.
The authors would like to give special thanks to N DeGroat for her assistance as study coordinator and C Auerbach for his review of earlier drafts of this manuscript.
Financial & competing interests disclosure
Award RC1HL100756 from the National Heart, Lung, and Blood Institute supported this research. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.
Ethical conduct of research
The authors state that they have obtained appropriate institutional review board approval or have followed the principles outlined in the Declaration of Helsinki for all human or animal experimental investigations. In addition, for investigations involving human subjects, informed consent has been obtained from the participants involved.
Personalized Medicine. 2014;11(7):631-640. © 2014 Future Medicine Ltd.