The REACT-2 trial is an international multicenter randomized clinical trial https://ClinicalTrials.gov/NCT01523626 to compare immediate total-body CT scanning during the primary survey of severely injured trauma patients with conventional imaging strategies supplemented by selective CT scanning.
The REACT-2 inclusion has started in April 2011. Results are expected in mid 2014.
ATLS: Advanced Trauma Life Support; AIS: Abbreviated Injury Score; AMC: Academic Medical Center; ED: Emergency Department; FAST: Focused Assessment with Sonography for Trauma; GCS: Glascow Coma Scale; ICU: Intensive Care Unit; mGy: Milligray; ISS: Injury Severity Score; mSv: Millisievert; REACT-2: Randomized study of Early Assessment by CT scanning in Trauma patients -2; CT: Computed Tomography.
ZonMw, the Netherlands organisation for health research and development (grant number: 1711020323) funded the REACT-2 trial.
JCS drafted the manuscript, TPS and JCG co-authored the writing of the manuscript. All authors participated actively in the design of the trial and critically appraised the manuscript. All authors read and approved the final manuscript.
BMC Emerg Med. 2012;12(4) © 2012 BioMed Central, Ltd.