Comparison of Intravenous and Oral Magnesium Replacement in Hospitalized Patients With Cardiovascular Disease

Brent N. Reed; Su Zhang, J. S. Marron; Deborah Montague


Am J Health Syst Pharm. 2012;69(14):1212-1217. 

In This Article


A comparison of 24-hour courses of magnesium replacement therapy showed that magnesium sulfate 2 g i.v. was associated with larger changes in SMC than magnesium oxide 800, 1200, or 1600 mg orally when the baseline SMC was 1.4–1.8 mg/dL. At baseline SMCs of 1.4–1.8 mg/dL, oral magnesium oxide provided a consistent median increase in SMC of 0.1 mg/dL. The change in the number of bowel movements did not differ significantly between courses of i.v. magnesium sulfate and oral magnesium oxide.


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