Management of Menorrhagia Associated With Chemotherapy-Induced Thrombocytopenia in Women With Hematologic Malignancy

Jill S. Bates, Pharm.D., M.S.; Larry W. Buie, Pharm.D.; C. Brock Woodis, Pharm.D.


Pharmacotherapy. 2011;31(11):1092-1110. 

In This Article

Menorrhagia Assessment Tools

Menstrual blood loss is a subjective, patientreported outcome that may not be easy to interpret. However, it is known that excessive blood loss does have a negative impact on quality of life. The National Institute for Health and Clinical Excellence has defined heavy menstrual bleeding as a health condition that "interferes with a woman's physical, social, emotional and/or material quality of life."[20] Numerous tools have been developed in an attempt to assess the effects of menorrhagia on quality of life; however, many of these tools have been nonspecific to heavy menstrual bleeding, lacked validity, and used unclear determinations of score. The Menorrhagia Impact Questionnaire (MIQ) was developed to identify measurement domains, define meaningful symptom relief, and measure magnitude of response (Table 2). The questionnaire assesses a patient's ability to perform physical functions, work, and participate in social and leisure activities, as well as measures global change in menstrual blood loss.[20,21]


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