Obesity and Wound Healing
Obesity predisposes to poor wound healing. Incisional hernias are one of the most common delayed complications.[25,26] Several clinical factors have been implicated, including an increased incidence of surgical wound infection, technical failure and haemorrhage. Leptin, the adipocytokine, promotes wound healing as well as inhibiting feeding and other immunological roles.[13,27,28] Leptin resistance, associated with obesity, may contribute to the pathophysiology of impaired wound repair.[13,27,28]
The British Journal of Dermatology. 2011;165(4):743-750. © 2011 Blackwell Publishing
Cite this: Obesity and the Skin - Medscape - Oct 01, 2011.