A.R. Shipman; G.W.M. Millington


The British Journal of Dermatology. 2011;165(4):743-750. 

In This Article

Obesity and Wound Healing

Obesity predisposes to poor wound healing.[24] Incisional hernias are one of the most common delayed complications.[25,26] Several clinical factors have been implicated, including an increased incidence of surgical wound infection, technical failure and haemorrhage.[25] Leptin, the adipocytokine, promotes wound healing as well as inhibiting feeding and other immunological roles.[13,27,28] Leptin resistance, associated with obesity, may contribute to the pathophysiology of impaired wound repair.[13,27,28]


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