Obesity and Wound Healing
Obesity predisposes to poor wound healing.[24] Incisional hernias are one of the most common delayed complications.[25,26] Several clinical factors have been implicated, including an increased incidence of surgical wound infection, technical failure and haemorrhage.[25] Leptin, the adipocytokine, promotes wound healing as well as inhibiting feeding and other immunological roles.[13,27,28] Leptin resistance, associated with obesity, may contribute to the pathophysiology of impaired wound repair.[13,27,28]
The British Journal of Dermatology. 2011;165(4):743-750. © 2011 Blackwell Publishing
Cite this: Obesity and the Skin - Medscape - Oct 01, 2011.
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