Obesity and Atopic Eczema
Obesity has been shown to alter the inflammatory state of an individual, leading to a low-level chronic inflammatory response and IL-6 secretion. There is an association between obesity, asthma and atopic eczema.[8,91,92] Mast cells can be synthesized from WAT, increased leptin levels correlate with allergen sensitization[93,94] and obesity correlates with skin infections.[7,83] All these observations could perhaps provide part of the pathogenic link between increased BMI and atopic eczema.
The British Journal of Dermatology. 2011;165(4):743-750. © 2011 Blackwell Publishing
Cite this: Obesity and the Skin - Medscape - Oct 01, 2011.