Bartonella Infection: Treatment and Drug Resistance

Silpak Biswas; Jean-Marc Rolain


Future Microbiol. 2010;5(11):1719-1731. 

In This Article


Bartonella species have a worldwide distribution. The most common Bartonella zoonosis worldwide is CSD, which is caused by B. henselae. Human cases have been reported on several continents, including North America, Europe and Australia. These bacteria are the most common Bartonella species detected in cats worldwide and are highly prevalent.[4,7–10] Humans are considered reservoir hosts for B. quintana and B. bacilliformis. B. bacilliformis is transmitted by sand fly species (Lutzomyia verrucarum) and B. quintana infections are transmitted by the body louse (Pediculus humanus).[1]B. henselae infection in cats was first reported in 1992,[11] and Bartonella vinsonii subsp. berkhoffii infection in dogs was reported in 1994.[12] Dogs are the mammalian reservoir for B. vinsonii subsp. berkhoffii, while dogs and foxes are the reservoirs for Bartonella rochalimae.[13] Several wild rodent-associated Bartonella species have been linked to human diseases, including Bartonella elizabethae, Bartonella grahamii, Bartonella vinsonii arupensis and Bartonella washoensis.