The burden of anemia and RBC transfusions in the PICU population are significant. The current guidelines for pediatric blood transfusions are mainly based on available information regarding transfusions in adults. Since many characteristics are specific to critically ill children and may affect the way in which they respond to anemia and transfusion, additional information is needed to better define guidelines for the prevention and treatment of anemia in this patient population. Pediatric transfusion medicine is evolving and incorporating new pharmacological agents into the armamentarium of anemia. For stable, critically ill children, there is increased evidence that a restrictive transfusion approach based on a predefined Hb value does not influence outcome. Continued research and large multicenter studies are needed to determine if, in high-risk patients, a symptomatic transfusion strategy is as effective, or possibly superior, to a Hb-based transfusion strategy.
Financial & competing interests disclosure
The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.
Pediatr Health. 2010;4(2):201-208. © 2010 Future Medicine Ltd.
Cite this: Transfusions in the Critically Ill Pediatric Patient - Medscape - Apr 01, 2010.