Should We Screen Preterm Infants for Nephrocalcinosis? An Evidence-based Decision

Shahirose S Premji; Majeeda Kamaluddeen


Pediatr Health. 2010;4(1):24-35. 

In This Article

Blood Pressure

A significantly higher percentage of premature infants with neonatal nephrocalcinosis have elevated systolic and diastolic blood pressure readings (defined as >95% percentiles of blood pressure against percentiles for length for healthy children) at 1-year and 2-year follow-up.[20] Saarela et al. reported increases (>97.5th percentile age-specific reference) in systolic and diastolic blood pressure at 4.7 years of age (SD ± 1 year) in a small number of premature infants with and without neonatal nephrocalcinosis.[26] Although Porter et al. report systolic hypertension in premature infants with nephrocalcinosis examined at a mean age of 6.9 years, it is not clear how systolic hypertension was defined.[29] When effected premature infants in the Schell-Feith et al.[20] study were followed at a mean age of 7.5 years (±1 year) and compared with preterm infants without nephrocalcinosis, there was no significant difference reported.[28]


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