The recommended dose of ursodiol for infants and children, based on clinical trials and case series, is 5 to 30 mg/kg/day, given in two or three divided doses.[2,5,6,7,8,9,10,11,12,13,14,15] In adults, the recommended dose is 300 mg given twice daily. For patient with primary biliary cirrhosis, the recommended dose is 13 to 15 mg/kg/day divided in 2 to 4 doses per day.[1,3]
Pediatr Pharm. 2009;15(2) © 2009 Children's Medical Center, University of Virginia
Cite this: Use of Ursodiol in Infants and Children - Medscape - Feb 01, 2009.