A Randomized Controlled Trial of Synchronized Nasal Intermittent Positive Pressure Ventilation in RDS

V Bhandari; R G Gavino; J H Nedrelow; P Pallela; A Salvador; R A Ehrenkranz; N L Brodsky;


December 05, 2007

In This Article

Statistical Analysis

Our primary outcome measure was the combined outcome of BPD or death. The initial target sample size for this study had been a total of 50 patients, but was revised to 41 due to the following reasons. The patient enrollment was terminated at AEMC when the site investigator (RG) left the institution in 2002. The enrollment was terminated at Yale site in 2005 due to potential conflict with the initiation of the NIH/NICHD-sponsored SUPPORT trial.

SNIPPV and CV groups were compared using Student's t-test, χ,1 Mann-Whitney U-test or repeated measures analyses of variance (ANOVAs), as appropriate. Statistical analyses were performed using SPSS 12.0 for Windows (SPSS Inc., Chicago, IL, USA). P<0.05 was considered statistically significant.


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