Hair Loss Induced by Lopinavir-Ritonavir

Joaquín Borrás-Blasco, Pharm.D., Ph.D.; Alberto Belda, M.D.; Dolores Rosique-Robles, Pharm.D., Ph.D.; Elvira Casterá, Pharm.D.; Javier Abad, Pharm.D., Ph.D.; Isabel Amorós-Quiles, M.D.


Pharmacotherapy. 2007;27(8):1215-1218. 

In This Article


Although lopinavir-ritonavir is considered to be safe, it has potential adverse effects. Generalized hair loss associated with this drug combination is rare. However, our patient's severe and generalized alopecia was probably induced by lopinavir-ritonavir. Clinicians should be aware of this adverse effect. If hair loss is severe or particularly distressing to the patient, the offending drug should be discontinued, and therapy with another HIV drug should be started.


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