Successful Treatment With Rasburicase of a Tophaceous Gout in a Patient Allergic to Allopurinol

Pascal Richette; Thomas Bardin


Nat Clin Pract Rheumatol. 2006;2(3):338-342. 

In This Article


Gout in postmenopausal women can have an atypical presentation, with numerous subcutaneous tophi of the hands and acute arthritis predominantly involving the upper limbs. In this case, the diagnosis of gout prompted a search for associated medical conditions such as hypertension, hyperlipidemia and diuretic intake. In this patient, who was intolerant to allopurinol, rasburicase therapy lowered serum-urate levels and appeared to promote rapid tophus dissolution.


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