Relapsing Polychondritis

Peter D. Kent; Clement J. Michet, Jr; Harvinder S. Luthra


Curr Opin Rheumatol. 2004;16(1) 

In This Article

Differential Diagnosis

Because of its rarity and attribution of symptoms to other coexistent disease, 1 or 2 years may elapse before the diagnosis is made. Auricular chondritis is relatively unique to relapsing polychondritis and eventually occurs in nearly 90% of cases. However, necrotizing external otitis resulting from Pseudomonas aeruginosa should always be considered in the patient with a unilateral inflamed ear.[57]

Various diseases can cause inflammatory or granulomatous lesions of the larynx and subglottic region, including Wegener granulomatosis, sarcoidosis, tuberculosis, amyloidosis, and rheumatoid arthritis.[58,59] The differential diagnosis of a saddle nose deformity includes Wegener granulomatosis, relapsing polychondritis, and rarely syphilis or leprosy.


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