Neonatal Lupus Erythematosus

Joanna M. Burch, Lela A. Lee and William L. Weston


Dermatology Nursing. 2002;14(3) 

In This Article

Heart Findings

Half of NLE neonates with have CHB. Most often the block is complete. Usually bradyarrythmias develop in utero, during the 2nd trimester (Lee & Weston, 1995). Bradyarrhythmia due to CHB can be detected before 30 weeks of gestation in 82% of cases. No severe structural abnormalities of the heart are generally found in association with CHB. The myocardium can also be affected in NLE. The major histologic finding in the heart is replacement of the AV nodal tissue with fibrosis. The most recent data review from the NLE registry by Buyon and colleagues revealed a 20% mortality rate with CHB. The majority of CHB deaths occurred in the first 3 months of life (Buyon et al., 1998). Sixty-three percent of children with CHB required pacemakers, the vast majority within the first year of life (Brucato et al., 1999).


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